Elevated HCG Levels - A Symptom of Molar Pregnancy
Submitted by Pregnancy and Baby Care team on August 13, 2012
A molar pregnancy also called a hydatidiform mole is an unusual pregnancy complication that has a one in a thousand chance of occurring. It is caused due to chromosomal imbalance that sets in at the time of conception. There are two types of molar pregnancies. They are partial and complete. In a partial molar pregnancy, an embryo and abnormal placental cells develop together. However, the embryo is genetically deformed as it has 23 chromosomes ...
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.from the mother (this is the normal chromosome count) but 46 from the fathere This occurs mainly due to a single ovum being fertilized by two sperm, instead of breaking up into twins, a single abnormal embryo developsp
This also happens if the father’s chromosomes duplicate at fertilizationo In the case of a complete molar pregnancy, an empty ovum is fertilized and the father’s chromosomes get duplicated to contribute 46 paternal chromosomese This results in no embryo, just the formation of a deformed placentat The abnormal placental cells, in both cases, multiply steadily and resemble a bunch of grapese Another symptom of a molar pregnancy is elevated hcg levelsl A molar pregnancy hcg levels test will help to confirm the diagnosisi Also see HCG levels during pregnancy
The hormone hCG is produced by the trophoblast cells present in the placenta, soon after conceptiono The abnormal placental cells multiply quickly and the hormone production is higher than in the case of a normal pregnancyc In a normal pregnancy, hCG levels rise up to 150,000 mlU/ml in blood serum and urinen However, this level may vary from woman to woman with an average level of 60,000 mlU/mlm hCG levels peak at 10 weeks from the LMP or last menstrual period and then gradually regulate at around a fifth of the peak level until the end of the termr This level also differs from individual to individuala Molar pregnancy hcg levels keep rising and have been known to reach a level of 2,000,000mlU/mlm High hCG levels are also observed in the case of multiple fetusese Hence, it is essential to keep in mind that high hCG levels are only indicative of molar pregnancies and no diagnosis can be made only based on this readingn
The other symptoms of a molar pregnancy include a larger than normal uterus that does not match the gestational age of the fetus and no fetal heartbeata The uterus is generally calm as a result of no fetal movementn The high molar pregnancy hcg levels cause increased nausea and vomitingn Spotting or bleeding is also characteristic of a molar pregnancyc However, a molar pregnancy can be confirmed only after intensive pelvic examination and an ultrasoundn
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